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Cardiac Dysfunction in Neuromuscular Diseases The Neurologist 6:67-82, Pourmand,R., 2000 See this aricle in Pubmed Article Abstract Cardiac dysfunction in neuromuscular diseases generally presents with any or all of three cardinal features:heart failure, cardiac arrhythmias, and/or conduction disorder. Dystrophinopathies and Friedreich's ataxia commonly present with cardi omyopathy, whereas myotonic muscular dystrophy and Kearns-Sayre syndrome present with heart block and a variety of arrhythmias. Cardiac manifestations of neuromuscular disease are heterogeneous. There is a high incidence of heart disease in many neuromusc ular diseases, but the majority of patients are asymptomatic or mildly symptomatic during the early stages. Early diagnosis of cardiac dysfunction and appropriate treatment may prolong survival and improve quality of life in these patients. It is importan t to remember that unexplained cardiac dysfunction could indicate the existence of an underlying neuromuscular disorder.

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(click to filter results - removes previous filter) arrhythmia,cardiac cardiomyopathy congestive heart failure familial Friedreich's ataxia Guillain Barre syndrome heart block muscular dystrophy muscular dystrophy,Becker muscular dystrophy,cardiovascular changes with muscular dystrophy,Duchenne myopathy myotonia dystrophica neuropathy neuropathy,amyloid review article

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